Wednesday, July 31, 2013

Crystallography Made Crystal Clear 3rd Edition, Gale Rhodes

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Crystallography Made Crystal Clear 3rd Edition: A Guide for Users of Macromolecular Models by Gale Rhodes provides clear, understandable descriptions of principles of X-ray crystallography. It leads reader through unintimidating and thorough explanations of the underlying mathematics. There are abundant illustrations, including diagrams, charts, photographs, and color stereo.

Author explains how to read crystallography papers in research journals by including brief descriptions of other diffraction methods (neutron, electron, Laue) and the kinds of structural information they can provide. This book introduces other methods of macromolecular structure determination (NMR spectroscopy and homology modeling), and provides guidance in judging the quality of these models.

Author makes crystallography accessible to readers who have no prior knowledge of the field, or its mathematical basis. It has been fully updated and expanded to make it the most comprehensive and concise reference for beginning crystallographers. The book also introduces essential World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers.

The CMCC Home Page provides access to all tools and links to all resources discussed in this book. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers.

Author provides guidance in quality control, with the hope of making you a prudent user of models from all sources. Neither of the new chapters contains full or rigorous treatments of these "other" methods. He gives you a useful feeling for these methods, for the relationship between data and structures, and for the pitfalls inherent in taking any model too literally.

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