HPLC for Pharmaceutical Scientists by Yuri V. Kazakevich and Rosario LoBrutto provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. It is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry.
In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided.
This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.
This guide is a valuable resource for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. A unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry is provided throughout the book.
In-depth discussions of retention processes, modern HPLC separation theory, and properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and numerous examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are given.
This book elucidates the role of HPLC throughout the entire drug development process, from drug candidate inception to marketed drug product, and gives detailed specifics of HPLC application at each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS—small molecules and proteins, LC-NMR, Preparative HPLC, High temperature HPLC, Chiral HPLC, and Fast LC) are discussed.
Authoritative and up to date, this book is an ideal reference for pharmaceutical researchers working with HPLC, as well as for graduate students in analytical chemistry/biochemistry and pharmaceutical analysis programs.
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